Investigator-Initiated Research

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SpringWorks is committed to supporting Investigator-Initiated Research (IIR) to advance medical and scientific knowledge relating to its product candidates and current therapeutic areas of interest.

Let’s learn together.

SpringWorks will consider unsolicited research proposals submitted electronically by external investigators interested in studying SpringWorks products or product candidates in therapeutic areas of interest.

SpringWorks will consider research proposals for clinical, preclinical, and non-interventional/observational studies as part of this program.

SpringWorks receives many requests for research support. Research support decisions are based on a careful evaluation of the scientific rigor of the research proposal, the expertise and track record of the investigator, the feasibility of supporting the research and the strategic interests of SpringWorks.

Interested investigators may submit research proposals for review by SpringWorks regarding the following product candidates:

  • Nirogacestat
  • Mirdametinib

†SpringWorks shall have no obligation to maintain the confidentiality of submitted research proposals and documents. This statement shall not supersede or otherwise affect the terms of any existing agreements between SpringWorks and the institution/investigator on whose behalf a research proposal is being submitted.

Committee meetings

All proposals will be reviewed by SpringWorks’ IIR Program Committee, which is comprised of a cross-functional team.

If approved, the IIR Program typically provides a research grant in the manner of funding and/or supply of study drug or materials. SpringWorks provides no guarantees that it will provide support for submitted proposals. The terms under which SpringWorks will provide support will be set forth in a written agreement.

The IIR Program Committee routinely meets to review IIR proposals. Proposals will be accepted on a rolling basis with no defined submission deadlines. Incomplete submissions may cause a delay in the Committee’s review and response.

Submission guidelines

Please complete the form below with as much information as possible (including by uploading a copy of the principal investigator’s curriculum vitae) and click “Submit” after reviewing the Terms & Conditions linked below. Fields marked with an asterisk (*) are preferred fields of information.

If you do not wish to use the form below, you may submit a concept proposal by using the “upload” feature at the bottom of this page and clicking “Submit”.